post translational modification ubiquitination
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Language: English Countries: United States
Ubiquitin is an around 8.5 kDa polypeptide comprising of 76 amino acids that is affixed to the ε-NH2 of lysine in target proteins by means of the C-terminal glycine of ubiquitin. Taking after an underlying monoubiquitination occasion, the arrangement of a ubiquitin polymer may happen, and polyubiquitinated proteins are then perceived by the 26S proteasome that catalyzes the debasement of the ubiquitinated protein and the reusing of ubiquitin.